Laurent Pouységu was born in Dax (France) in 1971. He studied chemistry at the University of Bordeaux (France), including a one-year training period at the University of the Basque Country (San Sebastian, Spain) as an Erasmus undergraduate student. He received his PhD in 1997 under the supervision of Prof. Bernard De Jéso for his work on structural determination in carbohydrate chemistry. He then joined Prof. Stéphane Quideau’s group as a post-doctoral fellow at Texas Tech University (Lubbock, USA), where he contributed to develop phenolic oxidative activation methodologies and ortho-quinol acetate-based chemistry for oxocyclization reactions. In 1998, he moved back to France, recruited by the University of Bordeaux as Maître de Conférences of Organic Chemistry in Prof. Quideau’s group. He continued and extended the investigations initiated in Texas, with a focus on the use of hypervalent iodine-based reagents (i.e., iodanes) in oxidative dearomatization of phenols for the total synthesis of bioactive natural products, including plant polyphenols, alkaloids, terpenoids and polyketides. In parallel, he developed a strong collaboration with research teams located at the University of Los Andes (Mérida) and at the University Central de Venezuela (Caracas), with the aim of promoting endemic medicinal plants and their specialized metabolites. In 2014, he was promoted to the rank of Professor (PR 2C) at the University of Bordeaux. His current research interests include i) the chemistry of chiral organoiodanes and their applications in asymmetric methodologies and total synthesis of natural products, ii) the synthesis and activities of plant polyphenols, as well as iii) the search for new bioactive compounds isolated from medicinal plants.